Spyre Therapeutics, Inc. (SYRE) Insider Trading

Spyre Therapeutics, Inc. (SYRE) has 12 SEC Form 4 insider filings on record in the last 90 days. No insider purchases were filed — 7 sales totalling $410.6M. Most recent filing: Sept. 3, 2026.

Filings
12
Purchases
0
$0
Sales
7
$410.6M
Insiders
7

Most active SYRE insiders

Fairmount Funds Management LLC
Director
0 bought · 1 sold · June 23, 2026
$399.7M
Burrows Scott L
Chief Financial Officer
0 bought · 1 sold · Sept. 3, 2026
$5.5M
Turtle Cameron
Chief Executive Officer
0 bought · 3 sold · Sept. 3, 2026
$4.1M
King-Jones Heidy
See Remarks
0 bought · 0 sold · Sept. 3, 2026
$2.9M
Albers Jeffrey W.
Director
0 bought · 1 sold · Aug. 10, 2026
$2.5M
HENDERSON MICHAEL THOMAS
Director
0 bought · 1 sold · June 23, 2026
$2.0M
Sloan Sheldon
Chief Medical Officer
0 bought · 0 sold · July 2, 2026
$960K

Latest SYRE Form 4 filings

Date Insider Value Shares Stake Pre-planned Links
Sept. 3, 2026 filed Sept. 1, 2026 Burrows Scott L Chief Financial Officer −$1,618,165 40,732 −19% Yes
Sept. 3, 2026 filed Sept. 1, 2026 King-Jones Heidy See Remarks 0 0% Yes
Sept. 3, 2026 filed Sept. 1, 2026 Turtle Cameron Chief Executive Officer −$1,309,410 15,000 −3% Yes
Aug. 10, 2026 filed Aug. 7, 2026 Albers Jeffrey W. Director −$1,881,540 33,000 −29% Yes
Aug. 5, 2026 filed Aug. 3, 2026 Burrows Scott L Chief Financial Officer $608,021 22,500 0% Yes

Showing the 5 most recent of 12 filings in the last 90 days.

About this data

Form 4 is the filing company officers, directors and 10% shareholders must submit to the SEC within two business days of trading their own company's stock. Open-market purchases generally carry more signal than sales, which are often scheduled in advance. More on how this works.

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